The French Gut at EMBL Human Microbiome Symposium 2025

Published: Sep 18, 2025 by FME Lab

The relationship between diet and the gut microbiome lies at the heart of both health and sustainability challenges. Understanding how dietary habits shape microbial diversity is key to developing new strategies for precision nutrition.

At the EMBL Human Microbiome Symposium, Julien had the pleasure of presenting preliminary results of the French Gut project, carried out at INRAE MetaGenoPolis in collaboration with AP-HP. This presentation sparked lively discussions, with many participants acknowledging the scale of the challenge: deploying such a project across the entire French territory.

The French Gut relies on an exceptional infrastructure, built thanks to the dedication of the entire MetaGenoPolis team. Their work made it possible to collect thousands of standardized dietary questionnaires, transform them into nutritional profiles, and link them with metagenomic data derived from stool samples. Their commitment to building this unique infrastructure is the backbone of the French Gut project. Bravo to the whole team!

From food spontaneous fermentations to food designed consortia

Our new article entitled “Microbiome metabolic modeling as a tool for innovation in fermented foods” has been published in in Current Opinion of Food Science¹.

Elham Karimi, Julien Tap, Marie-Christine Champomier-Vergès, Stéphane Chaillou. Microbiome metabolic modeling as a tool for innovation in fermented foods. Current Opinion of Food Science. 2025 ↩

The FME lab communicates about the links between the microbiome, nutrition and health.

On Thursday 27 November, the FME lab took part in the Food System Microbiomes Conference in Wageningen during the session dedicated to the connections between microbiomes, nutrition and health. The session was co-chaired by Stéphane Chaillou (INRAE, Micalis) and Prof. Christophe Courtin (KU Leuven), and provided an opportunity to showcase advances from two major European projects: DOMINO and HealthFerm.

Understanding How Fermented Foods Shape Health Insights From a New PIMENTO Review

A new scoping review published in Frontiers in Nutrition¹ as part of the COST Action PIMENTO initiative provides a comprehensive assessment of what is currently known about the health effects of fermented foods in specific human populations. This work reflects a substantial collective effort. We conducted an extensive and rigorous screening of the scientific literature, reviewing and selecting studies across many categories of fermented foods and health outcomes.

Humblot Christèle, Alvanoudi Panagiota, Alves Emilia, Assunçao Ricardo, Belovic Miona, Bulmus-Tuccar Tugce, Chassard Christophe, Derrien Muriel, Karagöz Mustafa Fevzi, Karakaya Sibel, Laranjo Marta, Mantzouridou Fani Th, Rosado Catarina, Pracer Smilja, Saar Helen, Tap Julien, Treven Primož, Vergères Guy, Pertziger Eugenia, Savary-Auzeloux Isabelle, A scoping review of the health effects of fermented foods in specific human populations and their potential role in precision nutrition: current knowledge and gaps. Frontiers in Nutrition. 2025 doi:10.3389/fnut.2025.1650633 ↩